Ceftazidime – Avibactam susceptibility among carbapenem-resistant Enterobacterales in a pilot study in Turkey
نویسندگان
چکیده
Abstract This study aimed to detect carbapenemase genes and determine the in vitro susceptibility of Ceftazidime-Avibactam (CZA) Enterobacterales isolates. Carbapenemase were detected by polymerase chain reaction. CZA sensitivity isolates was evaluated with broth microdilution (BMD) disk diffusion methods. A total 318 carbapenem-resistant included. Most ( n = 290, 91.2%) identified as Klebsiella pneumoniae . The most common type OXA-48 82, 27.6%). 84 KPC activity. Both BMD methods revealed that 95.2% sensitive CZA; whereas, 4 (4.76%) resistant CZA. Among colistin isolates, 96.5% 80) them susceptible Our demonstrated high efficacy producing carbapenemase. High rates against which generally are also pan drug resistant, makes a promising therapeutic choice for difficult-to-treat infections. Due its correlation BMD, method is suitable more practical detecting
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ژورنال
عنوان ژورنال: Acta microbiologica et immunologica Hungarica (Print)
سال: 2021
ISSN: ['1217-8950', '1588-2640']
DOI: https://doi.org/10.1556/030.2021.01525